Raw data of Metagenomic analysis of Tongxie Yaofang in treating rat model of ulcerative colitis with the "liver depression and spleen deficiency" syndrome

All rats were randomly divided into three groups: Control, Dinitrobenzene sulfonic acid (DNBS)-colitis, and DNBS+TXYF (n = 8). The physiological indexes of rats were detected. Compared with Control groups, a loss body weight, significant increased DAI score and CMDI score (P value < 0.01) were observed in rats from the DNBS-colitis group, indicating that the UC model was successfully established. Meanwhile, TXYF treatment significantly decreased the DAI score, CMID score, and TNF-α level (P value < 0.05).

将所有大鼠随机分为三组，每组8只（n=8），分别为对照组、二硝基苯磺酸（Dinitrobenzene sulfonic acid，DNBS）结肠炎模型组与DNBS联合TXYF干预组。本实验检测了各组大鼠的生理指标。与对照组相比，DNBS结肠炎模型组大鼠出现体重减轻，疾病活动指数（Disease Activity Index，DAI）与结肠黏膜损伤指数（Colonic Mucosal Damage Index，CMID）评分均显著升高（P < 0.01），提示溃疡性结肠炎（Ulcerative Colitis，UC）模型构建成功。同时，TXYF干预可显著降低DAI评分、CMID评分及肿瘤坏死因子-α（Tumor Necrosis Factor-α，TNF-α）水平（P < 0.05）。