Process Development of Halaven®: Synthesis of the C14–C35 Fragment via Iterative Nozaki–Hiyama–Kishi Reaction–Williamson Ether Cyclization
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http://www.thieme-connect.com/DOI/DOI?10.1055/s-0032-1317920
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资源简介：
Multikilogram manufacturing process of the Halaven® C14–C35 fragment is described. The synthesis features convergent assembly of subunits by iterative asymmetric Ni/Cr-mediated coupling executed in fixed equipment.
提供机构：
© Georg Thieme Verlag
创建时间：
2013-03-01
