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Asymmetric Synthesis of the Chlorocyclopropane-Containing Callipeltoside A Side Chain

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NIAID Data Ecosystem2026-03-06 收录
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https://figshare.com/articles/dataset/Asymmetric_Synthesis_of_the_Chlorocyclopropane-Containing_Callipeltoside_A_Side_Chain/3738606
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资源简介:
The callipeltoside A chlorocyclopropyl-containing dienyne side chain has been synthesized in nine steps and 33% overall yield from commercially available 1,2,5,6-O-dicyclohexylidene-d-mannitol. The key steps in the synthesis are a highly diastereoselective cyclopropanation of a vinyl chloride allylic ether and a Suzuki cross-coupling to complete the carbon framework.
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2016-08-20
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