Crystal structure of BACE1 with a pyrazole-substituted tetrahydropyran thioamidine
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Crystal structure of BACE1 with a pyrazole-substituted tetrahydropyran thioamidine Descriptor: (4aR,6R,8aS)-8a-(2,4-difluorophenyl)-6-(1-methyl-1H-pyrazol-4-yl)-4,4a,5,6,8,8a-hexahydropyrano[3,4-d][1,3]thiazin-2-amine, Beta-secretase 1, DIMETHYL SULFOXIDE, ... Authors: Parris, K.D, Pandit, J. Deposit date: 2015-01-30 Release date: 2015-04-01 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.86 Å) Cite: Utilizing Structures of CYP2D6 and BACE1 Complexes To Reduce Risk of Drug-Drug Interactions with a Novel Series of Centrally Efficacious BACE1 Inhibitors. J.Med.Chem., 58, 2015
创建时间：
2015-01-30
