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Crystal Structure Matriptase (C731S) in Complex with Inhibitor MM1132-2

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Protein Data Bank Japan2024-11-13 更新2026-04-19 收录
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Crystal Structure Matriptase (C731S) in Complex with Inhibitor MM1132-2 Descriptor: CHLORIDE ION, GLYCEROL, N~2~-{[3-(acetamidomethyl)phenyl]acetyl}-N-[(2S)-1-(1,3-benzothiazol-2-yl)-5-carbamimidamido-1,1-dihydroxypentan-2-yl]-L-leucinamide, ... Authors: Lovell, S, Kashipathy, M.M, Battaile, K.P, Janetka, J.W. Deposit date: 2023-02-03 Release date: 2024-07-10 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (1.35 Å) Cite: Use of protease substrate specificity screening in the rational design of selective protease inhibitors with unnatural amino acids: Application to HGFA, matriptase, and hepsin. Protein Sci., 33, 2024
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2023-02-03
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