Gene expression profile at single cell level of tumoral immune cells sorted from MB49 tumor tissues of wt and Lcn2 ko chimeric mice

Lcn2 was found as a marker of senescent neutrophils and to affect the tumor growth in our research. We used single cell RNA sequencing (scRNA-seq) to analyze the immune cells diversity and function change with Lcn2 knock-out Overall design: To investigate the the importance of Lcn2 to the neutrophils diversity and function, we performed single cell RNA-sequencing analysis by using BD Rhapsody system from immune cells sorted from MB49 tumor tissues of wt and Lcn2 ko chimeric mice