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Pacini et al identify selective gene dependencies from CRISPR screens in 930 cell lines. Using clinically curated multi-omics data and protein-protein interactions networks, they curate 370 candidate targets and estimate their prevalence in patient tumour cohorts. This enhances understanding of gene depenencies and comprehensively maps targetable cancer dependencies.
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Pacini, Clare创建时间：
2023-10-20
