Ischemia promotes hypertrophic nerve trunk formation and enteric neuron cell death in Hirschsprung's disease: Source data

Items Annotation ST-cluster_distrition.csv A table containing the number of ST-clusters across samples DEGs_C10_v_restCMusc.csv A table containing the result of DEG analysis for the comparison between ST cluster C10 and other muscular ST clusters (C8 and C9) DEGs_C13_v_C12.csv A table containing the result of DEG analysis for the comparison between ST cluster C13 (HNTs) and C12 (ganglia). DEGs_ST-cluster_total_marker.csv A table containing the markers for each ST cluster. DEGs_iMusc_ganglia_v_nMusc_ganglia.csv A table containing the result of DEG analysis for the comparison between ST iMusc_ganglia and nMusc_ganglia. DEGs_sc_all_markers.csv A table containing the markers of single-cell populations. DEGs_pseudotime_CLDN1.csv A table containing the results of gene differentially expressed during the differentiation from GREM1+ FLCs to CLDN1+ FLCs. Gene_set_score_for_C12_sub.csv A table containing the results of gene set score in the sub-population of ganglia (C12). scRNA-seq_reference_raw.RDS A Seurat object containing the raw count and meta matrix of the single-cell reference ST-seq_raw_count.txt.gz A raw count matrix of ST-seq data ST-spots_meta_info.txt A table containing the metainformation of ST-seq data Object_of_bulk_RNA-seq.RDS A Seurat object used to reproduce the results of gene set scores in bulk RNA-seq. ST-spots_cell_abundance.txt A table containing the abundance of single-cell populations in each ST-spot. Cell_trajectory_of_FLCs.RDS A Seurat object used to reproduce the results of the cell trajectory of fibroblast-like cells. p_value_scRNA-seq_abundance.xlsx A table containing the p-value of cell abundance across groups for single-cell populations CIBERSORT_CPM_count_matrix.txt A table containing the CMP matrix of bulk RNA-seq data for CIBERSORT CIBERSORT_ST_raw_matrix.txt A table containing the raw count matrix of ST-seq data for CIBERSORT scRNA-seq_distribution.csv A table containing the distribution of single-cell populations across the sample DEGs_FLC_APOD_across_group.csv A table containing the DEGs in the comparison among APOD+ FLCs in different groups Gene_set_score_for_sc_Pericyte.csv A table containing the results of gene set score in the single-cell population of pericytes Gene_set_score_for_sc_Endo_score.csv A table containing the results of gene set score in the single-cell population of endothelial cells ENC_FLC_vessel_interaction.RDS A Cellchat object used to reproduce the results of cell-cell interaction among ENCs, glial cells, APOD+ FLCs, CLDN1+ FLCs, perictyes, and vascular endothelial cells. Metainfor_FASTQ1.xlsx Metainformation of FASTQ files Metainfor_FASTQ2.xlsx Metainformation of FASTQ files