PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000632a
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PanDDA analysis group deposition -- Crystal structure of PTP1B in complex with compound_FMOPL000632a Descriptor: 1-methyl-5-(phenylamino)-1,2-dihydro-3H-pyrazol-3-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Tyrosine-protein phosphatase non-receptor type 1 Authors: Keedy, D.A, Hill, Z.B, Biel, J.T, Kang, E, Rettenmaier, T.J, Brandao-Neto, J, von Delft, F, Wells, J.A, Fraser, J.S. Deposit date: 2018-08-30 Release date: 2018-10-10 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.773 Å) Cite: An expanded allosteric network in PTP1B by multitemperature crystallography, fragment screening, and covalent tethering. Elife, 7, 2018
PanDDA分析小组存档数据集——PTP1B与化合物_FMOPL000632a结合的晶体结构。组分信息:1-甲基-5-(苯氨基)-1,2-二氢-3H-吡唑-3-酮、2-氨基-2-(羟甲基)丙烷-1,3-二醇,以及非受体型酪氨酸蛋白磷酸酶1型(Tyrosine-protein phosphatase non-receptor type 1)。作者:Keedy, D.A.、Hill, Z.B.、Biel, J.T.、Kang, E.、Rettenmaier, T.J.、Brandao-Neto, J.、von Delft, F.、Wells, J.A.、Fraser, J.S.。存档日期:2018年8月30日;发布日期:2018年10月10日;最后修改日期:2024年3月6日。实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率1.773埃。引用文献:《通过多温度晶体学、片段筛选与共价锚定技术解析PTP1B的扩展变构网络》,《eLife》,第7卷,2018年。



