Gene expression (Mean (ΔCt ± SD) of selected cytokines, signaling molecules and transcription factors associated with FOXP3+Treg and iTreg cells in skin lesions and M.leprae stimulated PBMC respectively in leprosy patients and healthy subjects.

p≤0.05 was considered as significant using Mann Whitney two tailed, non parametric test. Abbreviations: LL: lepromatous leprosy, BT: borderline tuberculoid leprosy. N: skin from normal subjects undergoing cosmetic surgery. HC: healthy household contacts. Figures in parenthesis indicate number of subjects studied. Skin:a BT vs LL pb LL vs N pc BT vs N pd LLvs HC pe BT vs HC pp