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This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
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2022-07-01
相关数据集
HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers
This SuperSeries is composed of the following subset Series: GSE38232: HSF1 drives a transcriptional program distinct from heat shock to support highly malignant human cancers [gene expression] GSE389
NIAID Data Ecosystem90
A precisely positioned MED12 activation helix stimulates CDK8 kinase activity. A precisely positioned MED12 activation helix stimulates CDK8 kinase activity
The Mediator kinase module regulates eukaryotic transcription by phosphorylating transcription-related targets and by modulating the association of Mediator and RNA Polymerase II. The activity of its
NIAID Data Ecosystem20
SFPQ promotes an oncogenic transcriptomic state in melanoma. SFPQ promotes an oncogenic transcriptomic state in melanoma
Analysis of SFPQ interactome in primary melanocytes and melanoma cells. Results provide insight into the oncogenic reprogamming of SFPQ-RNA interactome and especially the interactions with key melanom
NIAID Data Ecosystem10
Proteasome inhibition blocks estrogen-dependent gene transcription by decreasing histone H2B monoubiquitination in human breast cancer cells. Homo sapiens
The estrogen receptor-alpha (ERα) determines breast cancer cell phenotype and is a prognostic indicator. A better understanding of the mechanisms controlling ERα function may uncover improved strategi
NIAID Data Ecosystem40
PAF1c links S-phase progression to immune evasion and MYC function in pancreatic carcinoma [ChIP-seq/CUT&RUN]
In pancreatic ductal adenocarcinoma (PDAC), endogenous MYC is required for S-phase progression and escape from immune surveillance. Here we show that MYC in PDAC cells is needed for the recruitment of
NIAID Data Ecosystem10
