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The effect of mismatch repair impairment (msh-2 knockdown) on the mutation rates and spectra in C. elegans MA lines

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NIAID Data Ecosystem2026-05-10 收录
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C. elegans fog-2 knockout mutation accumulation lines (obligate outcrossers) were evolved for up to 50 generations with RNA interference of the msh-2 gene, rendering the mismatch repair mechanism defective

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2020-12-31
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