Biomarkers of hepatotoxicity induced by GF treatment.

Figshare2015-12-02 更新2026-04-29 收录

药物肝毒性

代谢标志物发现

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*Metabolite identified with database and commercially available references.**Metabolite identified with MS/MS fragment in the database and literature.

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2015-12-02

Effects of Methotrexate (MTX) and Sitagliptin (Sita) on oxidative stress markers in the liver.

药物肝毒性

氧化应激标志物

Effects of Methotrexate (MTX) and Sitagliptin (Sita) on oxidative stress markers in the liver.

NIAID Data Ecosystem60

Gene expression data from primary human hepatocytes treated with GGF2 for 6, 24, or 72 h or 24 h with a 48 h washout.

药物肝毒性

基因表达谱分析

GGF2 is a recombinant human neuregulin-1β in development for chronic heart failure. Phase 1 clinical trials of GGF2 were put on hold when transient elevations in serum aminotransferases and total bili

NIAID Data Ecosystem40

Gene expression profiles of HYDROX-cultured human liver organoids compared to those of Matrigel-cultured human liver organoids.. Gene expression profiles of HYDROX-cultured human liver organoids compared to those of Matrigel-cultured human liver organoids.

类器官培养

药物肝毒性

Human liver organoids, an in vitro 3D culture system to recapitulate biological tissue, are expected to be used for drug discovery. However, Matrigel, the most widely used extracellular matrix for org

NIAID Data Ecosystem20

Understanding Metabolic Alterations in Advanced Stage Chronic Kidney Disease Patients by NMR-based metabolomics

代谢标志物发现

慢性肾脏病代谢分析

Understanding metabolic alterations in CKD is crucial, as serum creatinine-based diagnosis lacks precision, affecting key clinical decisions. In this study, a 1H NMR-based metabolomics approach was em

Zenodo2025-02-05 更新40

Targeted metabolomics identifies high performing diagnostic and prognostic biomarkers for COVID-19

代谢标志物发现

COVID-19临床

The data contain all the baseline information about participants in the study (COVID-19 patients and non-COVID-19) as well as metabolite measurements made by targeted metabolomics (raw data COVID-19_S

Mendeley Data2021-06-04 更新20

Biomarkers of hepatotoxicity induced by GF treatment.

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