The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with LHSpTA peptide

The structure of the polo-box domain (PBD) of polo-like kinase 1 (Plk1) in complex with LHSpTA peptide Descriptor: Ac-LEU-HIS-SER-(TPO)-ALA, Serine/threonine-protein kinase PLK1 Authors: Kunciw, D.L, Rossmann, M, De Fusco, C, Spring, D.R, Hyvonen, M. Deposit date: 2017-03-16 Release date: 2018-05-16 Last modified: 2023-03-08 Method: X-RAY DIFFRACTION (1.809 Å) Cite: A cryptic hydrophobic pocket in the polo-box domain of the polo-like kinase PLK1 regulates substrate recognition and mitotic chromosome segregation. Sci Rep, 9, 2019

与LHSpTA肽结合的polo样激酶1（polo-like kinase 1, Plk1）的polo盒结构域（polo-box domain, PBD）的结构。肽描述：Ac-LEU-HIS-SER-(TPO)-ALA。该蛋白为丝氨酸/苏氨酸蛋白激酶PLK1（Serine/threonine-protein kinase PLK1）。作者：Kunciw, D.L、Rossmann, M、De Fusco, C、Spring, D.R、Hyvonen, M. 存档日期：2017-03-16；发布日期：2018-05-16；最后修改日期：2023-03-08。实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率1.809 Å）。引用文献：《polo样激酶PLK1的polo盒结构域中一个隐蔽疏水口袋调控底物识别与有丝分裂染色体分离》，《科学报告》（Sci Rep），第9卷，2019年。