Co-crystal structure of Chaetomium glucosidase with compound 23

Co-crystal structure of Chaetomium glucosidase with compound 23 Descriptor: (2R,3R,4R,5S)-1-(2-{6-[2-(4-azido-2-nitroanilino)ethyl]pyrazin-2-yl}ethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... Authors: Karade, S.S, Mariuzza, R.A. Deposit date: 2022-10-11 Release date: 2023-02-22 Last modified: 2024-11-13 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity. J.Med.Chem., 66, 2023毛壳菌（Chaetomium）葡糖苷酶与化合物23的共晶体结构 描述符：(2R,3R,4R,5S)-1-(2-{6-[2-(4-叠氮基-2-硝基苯胺基)乙基]吡嗪-2-基}乙基)-2-(羟甲基)哌啶-3,4,5-三醇、2-[双(2-羟乙基)氨基]-2-(羟甲基)丙烷-1,3-二醇、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖…… 作者：Karade, S.S.、Mariuzza, R.A. 存放日期：2022-10-11 发布日期：2023-02-22 最后修改日期：2024-11-13 实验方法：X射线衍射（分辨率2.3 Å） 引用文献：《具有抗SARS-CoV-2活性的内质网α-葡萄糖苷酶I强效亚氨基糖抑制剂的基于结构设计》，《J. Med. Chem.》，66卷，2023年