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Cross-species gene expression analysis of species-specific differences in preclinical assessment of pharmaceutical compounds

NIAID Data Ecosystem2026-03-07 收录

药物临床前评价

物种基因表达

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA208509 数据链接链接失效反馈

官方服务：

资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2013-06-14

物种基因表达

毒性评估

Significant qualitative and quantitative differences exist between humans and the animal models used in research. However, significant quantitative and qualitative differences exist between humans and

NIAID Data Ecosystem80

Additional file 2 of Epigenetic regulation of human-specific gene expression in the prefrontal cortex

神经细胞表观遗传学

物种基因表达

Additional file 2: Fig. S1. Species-specific expressed genes detected in RNA-seq and ssRNA-seq datasets.Overlap of human-, chimpanzee-, and macaque-specific genes detected in RNA-seq and ssRNA-seq.Pea

Figshare2024-09-11 更新40

Data_Sheet_2_Meta-Analysis of Preclinical Studies of Fibrinolytic Therapy for Acute Lung Injury.xlsx

急性肺损伤

药物临床前评价

BackgroundAcute lung injury (ALI) is characterized by suppressed fibrinolytic activity in bronchoalveolar lavage fluid (BALF) attributed to elevated plasminogen activator inhibitor-1 (PAI-1). Restorin

NIAID Data Ecosystem20

Invasive Florida Python bivittatus small intestine mRNA sequencing. Python bivittatus

物种基因表达

消化生理学

mRNAseq data from the small intestine of fasted Python bivittatus from the invasive population in Florida.

NIAID Data Ecosystem50

Functional characterization of a novel 3D model of the epithelial-mesenchymal trophic unit

气道疾病

药物临床前评价

Background/Aim: Epithelial-mesenchymal communication plays a key role in tissue homeostasis and abnormal signaling contributes to chronic airways disease such as COPD. Most in vitro models are limited

NIAID Data Ecosystem30

Cross-species gene expression analysis of species-specific differences in preclinical assessment of pharmaceutical compounds

资源简介：

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