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A dataset of human and Plasmodium falciparum genotypes in severe malaria cases from The Gambia and Kenya

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NIAID Data Ecosystem2026-03-13 收录
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https://zenodo.org/record/4973476
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This data release contains human and Plasmodium falciparum malaria genotypes from the article: Malaria protection due to sickle haemoglobin depends on parasite genotype Gavin Band, Ellen M. Leffler, Muminatou Jallow, Fatoumatta Sisay-Joof, Carolyne M. Ndila, Alexander W. Macharia, Christina Hubbart, Anna E. Jeffreys, Kate Rowlands, Thuy Nguyen, Sónia Gonçalves, Cristina V. Ariani, Jim Stalker, Richard D. Pearson, Roberto Amato, Eleanor Drury, Giorgio Sirugo, Umberto d'Alessandro, Kalifa A. Bojang, Kevin Marsh, Norbert Peshu, Joseph W. Saelens, Mahamadou Diakité, Steve M. Taylor10, David J. Conway, Thomas N. Williams, Kirk A. Rockett, Dominic P. Kwiatkowski Nature (2021) doi: 10.1038/s41586-021-04288-3 bioRxiv link: doi.org/10.1101/2021.03.30.437659. The release contains genotypes from human and Plasmodium falciparum genetic variants, genotyped using blood samples from 4,171 children ascertained with severe symptoms of malaria at the Royal Victoria Teaching Hospital (now the Edward Francis Small Teaching Hospital), The Gambia, and from the Kilifi District Hospital (now Kilifi County Hospital), Kenya in the period 1995-2009. An accompanying set of association test summary statistics has also been released on Zenodo (doi: 10.5281/zenodo.5722497).  Please see www.malariagen.net/resource/32 for full details of other resources associated with the above manuscript.
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2021-12-09
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