DYRK2 gene transfer suppresses liver tumorigenesis
收藏NIAID Data Ecosystem2026-05-01 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE214053
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We generated liver-specific Dyrk2 knockout mice mating Dyrk2 flox mice with Alb-cre mice and co-introduced SB13-transposase-, myrAkt-, Myc- and mutant Hras-expressing plasmids with either HA- or Dyrk2-expressing plasmid into the knockout mice by HTVi. Dyrk2-expressing suppressed tumorigenesis compared with HA-expressing. Total RNAs from Dyrk2-expressed HCC in 3 Dyrk2 LKO mice were compared with Total RNAs from HA-expressed HCC in 3 Dyrk2 LKO mice.
创建时间：
2023-09-08
