A mini-hairpin shaped nascent peptide blocks translation termination by a distinct mechanism
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Distal nucleotides affect the rate of stop codon read-through
A key step in gene expression is the recognition of the stop codon to terminate translation at the correct position. However, it has been observed that ribosomes can misintrepret the stop codon and co
NIAID Data Ecosystem50
UAG readthrough in mammalian cells: Effect of upstream and downstream stop codon contexts reveal different signals
BACKGROUND: Translation termination is mediated through an interaction between the release factors eRF1 and eRF3 and the stop codon within its nucleotide context. Although it is well known that the nu
PubMed Central2001-02-27 更新40
Distal nucleotides affect the rate of stop codon read-through
A key step in gene expression is the recognition of the stop codon to terminate translation at the correct position. However, it has been observed that ribosomes can misintrepret the stop codon and co
Zenodo2021-05-04 更新20
Codon and anticodon immediately upstream of the stop codon (−1 position).
Codons at −1 of these sequences are recognized by the same tRNA. In bold, the original nucleotide at −1 position and the Wobble pairing.
Figshare2015-12-02 更新50
Stop Codon Context Influences Genome-Wide Stimulation of Termination Codon Readthrough by Aminoglycosides [Dataset 3]
Stop codon readthrough (SCR) occurs when the ribosome miscodes at a stop codon. Such readthrough events can be therapeutically desirable when a premature termination codon (PTC) is found in a critical
NIAID Data Ecosystem40



