Effect of deleting PexRAP/ADHAPR in adipose tissue of chow-fed male C57/BL6J mice

To investigate the role of PexRAP/ADHAPR in adipose tissue, we use adiponectin-driven Cre recombinase to delete Dhrs7b, the gene which encodes PexRAP/ADHAPR, from all adipose depots. This study assays gene expression in subcutaneous adipose tissue (iWAT) of 8 week old chow-fed male mice. We performed gene expression profiling analysis using data obtained from RNA-seq of iWAT tissue from either cre-negative (control) or cre-positive (PexRAP-AKO) male chow-fed mice