ViroDyn Ulcerative Colitis GWAS Atlas v1.0.0
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This Zenodo record contains ViroDyn Ulcerative Colitis GWAS Atlas v1.0.0, a versioned, machine-readable atlas of ulcerative colitis genetics centred on the GWAS Catalog trait ulcerative colitis (EFO_0000729). The release integrates live GWAS Catalog study enumeration with GWAS Catalog top hits, alongside a comprehensive suite of downstream resources. These include a machine-readable summary statistics manifest, mirrored redistributable harmonised summary statistics, locus definitions, credible sets, variant consequence and variant-to-gene mapping, gene prioritisation scores, pathway and network context, therapeutic target overlays, controlled-access manifests, quality control reports, checksums, and a query-ready DuckDB bundle. Version 1.0.0 contains: 184 study registry rows 2,282 top-hit rows 67 summary statistics manifest rows 53 mirrored harmonised study partitions comprising 793,314,938 harmonised association rows 2,621 loci 5,614 credible set rows 1,446 variants 37,398 variant-to-gene mapping rows 3,493 gene score rows The canonical release build is GRCh38, with GRCh37 compatibility retained where available. Controlled-access resources are represented as manifests rather than redistributed data. Linked external assets, including Pan-UK Biobank and FinnGen, remain explicit external references within the release metadata. This record is designed to support reproducible ulcerative colitis GWAS discovery, locus follow-up, replication review, variant-to-gene interpretation, target prioritisation, and AI-assisted downstream analysis. Users should cite this atlas alongside the GWAS Catalog, Open Targets, and the original study publications when making study-specific or biological claims.



