Gene expression analysis on melanoma cell lines and effects of NIPBL depletion

Gene expression was studied in melanoma cell lines with (SKMEL-23 and SKMEL-1128) or without (A375 and CLOL800) ALKATI expression. Effects on gene expression was also analyzed after knockdown of NIPBL in melanoma cell lines 501mel, COLO800 and A375 Overall design: RNA-seq was performed on SKMEL-23, SKMEL-1128, A375 and COLO800 without treatment. RNA-seq was performed on shLuc, shNIPBL_#1, shNIPBL_#2 knockdown cells for 501mel, COLO800 and A375