A Chinese host genetic study discovered IFNs and causality of laboratory traits on COVID-19 severity ,A study of Zhu et al
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Supplementary Tables from the study: one-sample and two-sample Mendelian randomization studies of white blood cell counts (WBC) and low-density lipoprotein cholesterol (LDL-C) on COVID-19 susceptibility and severity with summary statistics obtained from East Asian and European populations, two-sample reverse Mendelian randomization studies with exposure variable as COVID-19 disease and outcome variable as WBC and LDL-C. In details,
Table S1. Seven top SNP-trait significant associations and the corresponding one-sample and two-sample MR results with COVID-19 severity obtained from our dataset, related to Figure 4.
Table S2. Two-sample MR results with SNP-exposure summary statistics from our dataset and SNP-outcome summary statistics from HGI database, related to Figure 4.
Table S3. Two-sample MR results based on one WBC-associated SNP in gene HLA-C from an EAS study and SNP-outcome summary statistics from HGI database, related to Figure 5.
Table S4. Summary statistics of a list of WBC-related SNPs in an EAS population and their associations in HGI and the corresponding two-sample MR results, related to Figure 5.
Table S5. Two-sample MR results based on one LDL.C-associated SNP in gene ApoE from an EAS study and SNP-outcome summary statistics from HGI database, related to Figure 5.
Table S6. Summary statistics of a list of LDL.C-related SNPs in an EAS population and their associations in HGI and the corresponding two-sample MR results, related to Figure 5.
Table S7. Two-sample MR results based on one WBC-associated SNP in gene HLA-DPA1/HLA-DPB1 from an EUR study and SNP-outcome summary statistics from HGI database, related to Figure 5.
Table S8. Summary statistics of a list of WBC-related SNPs in an EUR population and their associations in HGI and the corresponding two-sample MR results, related to Figure 5.
Table S9. Two-sample MR results based on one LDL.C-associated SNP in gene ApoE from an EUR study and SNP-outcome summary statistics from HGI database, related to Figure 5.
Table S10. Summary statistics of a list of LDL.C-related SNPs in an EUR population and their associations in HGI and the corresponding two-sample MR results, related to Figure 5.
Table S11. Summary statistics of a list of COVID19-related SNPs from the HGI database and their associations with WBC in our dataset and the corresponding two-sample MR results, related to Table 3.
Table S12. Summary statistics of a list of COVID19-related SNPs from the HGI database and their associations with LDL-C in our dataset and the corresponding two-sample MR results, related to Table 3.
Table S13. Summary statistics of a list of COVID19-related SNPs from the HGI database and their associations with WBC in an UKBB study and the corresponding two-sample MR results, related to Table 3.
Table S14. Summary statistics of a list of COVID19-related SNPs from the HGI database and their associations with LDL-C in an UKBB study and the corresponding two-sample MR results, related to Table 3.
创建时间:
2021-09-22



