Multivariate linear regression models to investigate associations between beneficial responses, entropy, HLA alleles and % inhibition (dependent variable).

In each model, magnitude = total beneficial response (sum of responses to beneficial peptide pools) Ratio of protective / total response = total beneficial response / total proteome response (both defined as IFN-γ+ cells/million CD8+ T cells) * HLA-B*27, B*51, B*5701, B*5801, B*81 § HLA-B*35 (Py), HLA-B*53 Multivariate linear regression models to investigate associations between beneficial responses, entropy, HLA alleles and % inhibition (dependent variable).