Nano drug-delivery systems for management of AIDS: liposomes, dendrimers, gold and silver nanoparticles Supplementary Dataset

AIDS causes increasing mortality every year.With advancements in nanomedicine, different nanomaterials
(NMs) have been applied to treat AIDS and overcome its limitations. Among different NMs, nanoparticles
(NPs) can act as nanocarriers due to their enhanced solubility, sustained release, targeting abilities
and facilitation of drug dose reductions. This review discusses recent advancements in therapeutics for
AIDS/HIV using various NMs, mainly focused on three classifications: polymeric, liposomal and inorganic
NMs. Polymeric dendrimers, polyethylenimine-NPs, poly(lactic-co-glycolic acid)-NPs, chitosan and the use
of liposomal-based delivery systems and inorganic NPs, including gold and silver NPs, are explored. Recent
advances, current challenges and future perspectives on the use of these NMs for better management of
HIV/AIDS are also discussed.