Distinct microglia subsets are associated with α-synucleinopathy in multiple system atrophy
收藏NIAID Data Ecosystem2026-05-10 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE209944
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资源简介：
We developed a novel mice model of multiple system atrophy (MSA)-cerebellar type (MSA-C) by over-expression of human mutant α-synuclein (α-syn) in oligodendrocyte using Tet-off system. We identified distinct microglial subpopulations in a novel MSA-C model mice. mRNA profiles of CD11b-positive microglia from the brains of Tg mice before MSA-C onset, Tg mice after MSA-C onset, and Tg mice treated with BLZ945.
创建时间：
2025-09-17
