Highly Regioselective, Acid-Catalyzed, Three-Component Cascade Reaction for the Synthesis of 2‑aminopyridine-Decorated Imidazo[1,2‑<i>a</i>]pyridine
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A highly regioselective acid-catalyzed three-component reaction of 2-aminopyridine and 3-phenylpropiolaldehyde for the construction of imidazo[1,2-a]pyridine has been developed. This strategy provides a broad range of substrates and represents an efficient approach to give various 2-aminopyridine-decorated imidazo[1,2-a]pyridine in good yields.
创建时间:
2019-01-22



