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Highly Regioselective, Acid-Catalyzed, Three-Component Cascade Reaction for the Synthesis of 2‑aminopyridine-Decorated Imidazo[1,2‑<i>a</i>]pyridine

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A highly regioselective acid-catalyzed three-component reaction of 2-aminopyridine and 3-phenylpropiolaldehyde for the construction of imidazo­[1,2-a]­pyridine has been developed. This strategy provides a broad range of substrates and represents an efficient approach to give various 2-aminopyridine-decorated imidazo­[1,2-a]­pyridine in good yields.

创建时间:
2019-01-22
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