Synthesis and PKC Binding of a New Class of A-Ring Diversifiable Bryostatin Analogues Utilizing a Double Asymmetric Hydrogenation and Cross-Coupling Strategy
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https://figshare.com/articles/dataset/Synthesis_and_PKC_Binding_of_a_New_Class_of_A_Ring_Diversifiable_Bryostatin_Analogues_Utilizing_a_Double_Asymmetric_Hydrogenation_and_Cross_Coupling_Strategy/3057184
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资源简介：
The design, asymmetric synthesis, and biological evaluation of a new class of bryostatin analogues based on a pseudosymmetric spacer
domain are described. An aryl bromide diversification site is incorporated allowing access to systematically varied analogues. The new analogues
all exhibit potent, nanomolar affinity to PKC.
创建时间：
2006-09-28
