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Histone demethylation and MYC activation enhance translational capacity in response to amino acid restriction. Histone demethylation and MYC activation enhance translational capacity in response to amino acid restriction

NIAID Data Ecosystem2026-03-10 收录

组蛋白去甲基化

翻译调控

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA391293 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2017-06-21

细胞分化

组蛋白去甲基化

Base on the privious studie from our lab, we found the histone demethylases, Jmjd2a and Jmjd2c are upregulated in stimulated primary B cells, depletion of Jmjd2a and Jmjd2c in stimulated B cells resul

NIAID Data Ecosystem60

Global analysis of the actively translating portion of the transcriptome of control and YBX1 depleted proliferating epidermal cells by high-resolution RNA-seq analysis

翻译调控

内皮细胞增殖

To investigate the mechanisms underlying the effects of YBX1 depletion on epidermal progenitors, we performed deep RNA-seq analysis of control versus YBX1-depleted proliferating epidermal cells. Since

NIAID Data Ecosystem50

Ribosome profiling (Ribo-Seq) and mRNA sequencing (RNA-Seq) of Human leukemia monocytic cell line (THP-1) cells upon treatment with LPS and LPS+dexamethasone (Dex).. Ribosome profiling (Ribo-Seq) and mRNA sequencing (RNA-Seq) of Human leukemia monocytic cell line (THP-1) cells upon treatment with LPS and LPS+dexamethasone (Dex).

核糖体谱分析

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THP-1 cells were treated with vehicle control (0.1% ethanol/PBS), LPS and LPS+Dex for 3 hr. We then performed combined analysis of ribosome footprints (RPF) and mRNA abundance using the data obtained

NIAID Data Ecosystem40

Translational profiling in multiple myeloma to identify novel therapeutic targets. Homo sapiens

多发性骨髓瘤

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The goal of this study is to identify translationally-regulated mRNAs in multiple myeloma following treatment with dexamethasone Overall design: The overall design is to treat the multiple myeloma cel

NIAID Data Ecosystem60

Ribosome profiling data of HEK293T cells treated with C13-benzamidyl cycloheximide

核糖体谱分析

翻译调控

We performed ribosome profiling in HEK293T cells with treatment with either C13-benzamidyl cycloheximide (hereafter "benzamide") or cycloheximide. Overall design: In order to evaluate the effect that

NIAID Data Ecosystem50

Histone demethylation and MYC activation enhance translational capacity in response to amino acid restriction. Histone demethylation and MYC activation enhance translational capacity in response to amino acid restriction

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