The ability to avoid relapse to opioid use is sexually dimorphic and challenging partly because of the co-morbid sleep disruption that occurs. The hypothalamic-pituitary adrenal (HPA) axis is thought
The global literature about rapid-onset opioids (ROOs) was scanned in the Web of Science online database. The search terms and string applied to identify the closest matching articles included “rapid-
The main factors and the interactions are reported in the first column. The F values, the related degrees of freedom (df), the associated p values (in bold are reported those which are
