Human cytomegalovirus UL40 signal sequencing, Clinical studies of UL40 signal sequence diversity on blood and intraocular fluids of Japanese patients

Human cytomegalovirus (HCMV) infections develop into CMV diseases that manifest as various forms in local organs. To investigate differences of HCMV circulating in the peripheral blood and in local tissues, polymorphisms of UL40 virus gene were analyzed in blood and intraocular fluids of Japanese clinical specimens positive for human cytomegalovirus using targeted deep amplicon sequencing.