Base editors, mainly including cytidine base editors(CBE) and adenine base editors(ABE), have been widely used to modify single-base in genomic DNA. The efficiency of A-to-G towards the PAM for ABE an
Frequencies of targeted foreign DNA integration events derived from Southern blot analysis of dHV.68/5′3′.F50-transduced HeLa cell and DMD myoblast clones.
Processed data for self-targeting adenine base editor screens performed in human K562 and HEK293T cells. Reports the percentage of reads with edits for each guide when using each editor.
Additional file 4. Contains additional informations to primers, oligonucleotide pool, ABE sequences and editing efficiency per position for all relevant datasets of this study.
