Novel loci not previously reported to colocalise with liver eQTL, but colocalising based on our analysis.

Signals previously not reported as having a probable shared variant but supported by our method based on PP4 (posterior probability for a shared signal) >75% for colocalisation between the liver eQTL dataset and the Teslovich et al. meta-analysis of LDL, HDL, TG, TC, using the strict prior . For 11 genes with strong candidate status for lipid metabolism, we list a key reference that describes their function (see Text S2 for more details of gene functions).