Salmonella enterica subsp. enterica serovar Typhimurium Genome sequencing and assembly. Salmonella enterica subsp. enterica serovar Typhimurium

The Lilliengeen type (LT) collection of Salmonella enterica serovar Typhimurium has served the scientific community as both a model organism for basic genetic and biochemical pathway research (LT2), a mutator strain (LT7), and a source of bacteriophage (bacteriophage P22 isolated from Salmonella LT22 host) that was constructed into the default tool (P22HTint) for transducing DNA from one Salmonella strain to another, or back crossing mutations into wild-type backgrounds to confirm phenotypes. Inasmuch as LT2, LT7, and LT22 has contributed so much to scientific advancement in the last 65 years, the question arises whether any of the other strains in the Lilliengeen collection have characteristics that could further discoveries in molecular genetics. Our laboratory took the original LT strains and performed microarray assays over a decade ago to determine which of the strains were particularly unique compared to the published LT2 sequence. Here we report the draft genome sequences of the unique Lilliengeen type Salmonella enterica serovar Typhimurium strains LT1, LT18, LT19, LT20, LT21, and LT22.