Supplementary Material for: Side Effects’ Frequency Assessment of low dose oral minoxidil in male androgenetic alopecia patients

Introduction: Hair loss is a very common complaint in dermatologists' offices, requiring the use of proven safe and effective therapies to improve the condition without jeopardizing patients’ health and well-being. Methods: We selected 100 male patients with androgenetic alopecia beginning treatment with oral minoxidil (dosage: 0,5mg - to 5 mg) to observe incidence and frequency of side effects. Results: The side-effects/symptoms observed in the assessed patients included body and facial hypertrichosis (most incident – 16 and 11% respectively), lower legs oedema (4%), periorbital oedema (4%), fatigue (1%), tachycardia (1%), and insomnia (3%). Dizziness, hypotension, respiratory changes, and diarrhea were expected although not found in the assessed participants. No life-threatening adverse effects were observed. Conclusion: the doses administered in current research of oral minoxidil presented good safety profile as hair loss treatment, with the most incident side-effect being related to hypertrichosis. Systemic side-effects were infrequent.