The sensitivity of malignant tissues to T cell-based cancer immunotherapies is dependent on the presence of targetable HLA class I ligands on the tumor cell surface. Peptide intrinsic factors, such as
Considering the well established role of nonclassical HLA-G class I molecules in inhibiting natural killer (NK) cell function, the consequence of abnormal HLA-G expression in malignant cells should be
Standardisation of Immunopeptidomics experiments across laboratories is a pressing issue within the field, and currently a variety of different methods for sample preparation and data analysis tools a
For each region, HLA types for which there are reported and predicted epitopes in the Los Alamos HIV Immunology Database (http://www.hiv.lanl.gov/content/sequence/ELF/epitope_analyzer.html) are listed
aHLA-C allele designations follow the classification scheme of release 2.14.1 (Aug 2006) of the IMGT/HLA Sequence Database maintained by the HLA Informatics Group of the Anthony Nolan Research Institu
