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Rapid Synthesis of Polyprenylated Acylphloroglucinol Analogs via Dearomative Conjunctive Allylic Annulation

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Figshare2015-12-17 更新2026-04-29 收录
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https://figshare.com/articles/dataset/Rapid_Synthesis_of_Polyprenylated_Acylphloroglucinol_Analogs_via_Dearomative_Conjunctive_Allylic_Annulation/2038191
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资源简介:
Polyprenylated acylphloroglucinols (PPAPs) are structurally complex natural products with promising biological activities. Herein, we present a biosynthesis-inspired, diversity-oriented synthesis approach for rapid construction of PPAP analogs via double decarboxylative allylation (DcA) of acylphloroglucinol scaffolds to access allyl-desoxyhumulones followed by dearomative conjunctive allylic alkylation (DCAA).
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2015-12-17
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