Power Estimates () for the three approaches: collapsing (C) versus weighted-sum (WS) versus replication-based (R).
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Two genetic simulation models are assumed: neutral variants (1), and mildly deleterious variants (2). Varying number of DSVs are assumed, that can contribute equally or unequally to the total PAR. The sample size is the total number of individuals sequenced, with equal numbers of cases and controls. All tests are two-sided, i.e., testing for the presence of risk or protective variants in the region of interest.
创建时间:
2011-02-03



