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Role of N-a-acetyltransferase 10 Protein in DNA Methylation and Genomic Imprinting

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NIAID Data Ecosystem2026-05-17 收录
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We report that Naa10-null mice display partial embryonic lethality, growth retardation, brain disorder and maternal-effect lethality, phenotypes commonly observed in defective genomic imprinting. Genome-wide analyses further reveal enriched dysregulation of imprinted genes in Naa10p-knockout ES cells. Overall design: mRNA profiles of 2 biological ESC replicates of each WT and Naa10-KO group

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2017-10-11
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