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Difference between sulforaphane and sulforaphene in colon cancer

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE174444
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Sulforaphane and sulforaphene are isothiocyanate compounds derived from cruciferous vegetables that have demonstrated antiproliferative properties against colon cancer. However, the underlying mechanism of action of these two compounds is yet to be elucidated. The present study aimed to study the effects of sulforaphane and sulforaphene on colon cancer by next-generation sequencing (NGS). The colon cancer cell line, SW480, was cultured with 25 μmol/l sulforaphane and sulforaphene. Total RNA was extracted following 48 h of incubation of the cells with the compounds and NGS was performed with Clariom S Array.
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2021-08-30
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