Tumor mutation burden is an imperfect proxy of tumor foreignness and has therefore failed to consistently demonstrate clinical utility in predicting responses in the context of immunotherapy. We evalu
Summary This metadata record provides details of the data supporting the claims of the related manuscript: “Inflation of Tumor Mutation Burden by Tumor-Only Sequencing in Under-Represented
Mutational load is the depression in a population's mean fitness that results from the continual influx of deleterious mutations. Here, we directly estimate the mutational load in a population of hapl
Table S5. Empirical analysis of TMB association or predictive value for immunotherapy response. These analyses were performed on panel-based TMB values, directly calculated by panel sequencing. The ta
Additional file 4. Tumor suppressor genes for which nonsense SNVs and SNPEff impact ratings of “HIGH”, “MODERATE”, or “LOW” variants are excluded from CDS counts.
