Full length Glycine receptor reconstituted in lipid nanodisc in Gly/IVM-conformation (State-3)
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Full length Glycine receptor reconstituted in lipid nanodisc in Gly/IVM-conformation (State-3) Descriptor: (2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-butan-2-yl]-20,20b-dihydroxy-5',6,8,19-tetramethyl-17 -oxo-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-tetradecahydro-2H,7H-spiro[11,15-methanofuro[4,3,2-pq][2,6]benzodioxacy clooctadecine-13,2'-pyran]-7-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-alpha-L-arabino-hexopyranosyl)-3-O-methyl-alpha-L-arabino-hexopyranoside, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, GLYCINE, ... Authors: Kumar, A, Basak, S, Chakrapani, S. Deposit date: 2020-01-27 Release date: 2020-07-29 Last modified: 2025-05-21 Method: ELECTRON MICROSCOPY (3.07 Å) Cite: Mechanisms of activation and desensitization of full-length glycine receptor in lipid nanodiscs. Nat Commun, 11, 2020
脂纳米盘(lipid nanodisc)中重构的全长甘氨酸受体(glycine receptor),处于Gly/IVM构象(状态3)
描述符:(2aE,4E,5'S,6S,6'R,7S,8E,11R,13R,15S,17aR,20R,20aR,20bS)-6'-[(2S)-2-丁基]-20,20b-二羟基-5',6,8,19-四甲基-17-氧代-3',4',5',6,6',10,11,14,15,17,17a,20,20a,20b-十四氢-2H,7H-螺[11,15-甲酰呋喃并[4,3,2-pq][2,6]苯并二氧环十八碳烯-13,2'-吡喃]-7-基 2,6-二脱氧-4-O-(2,6-二脱氧-3-O-甲基-α-L-阿拉伯型己吡喃糖基)-3-O-甲基-α-L-阿拉伯型己吡喃糖苷、2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖-(1→4)-2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖、甘氨酸……
作者:Kumar A、Basak S、Chakrapani S
提交日期:2020年1月27日
发布日期:2020年7月29日
最后修改日期:2025年5月21日
实验方法:电子显微镜(3.07埃)
引用文献:《脂纳米盘中全长甘氨酸受体的激活与脱敏机制》,《自然-通讯》(Nat Commun),第11卷,2020年
创建时间:
2020-01-27



