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PiggyBac (PB) genetic screening allows identification of putative metastatic genes

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NIAID Data Ecosystem2026-03-12 收录
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https://www.ncbi.nlm.nih.gov/sra/SRP247608
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Next-Generation Sequencing was applied to investigate candidate breast cancer metastatic genes. PB targeted sequencing of primary tumours and metastases (3 lung metastases, 6 lung macro-metastases and 9 LM cell lines) allowed to identify Nfib as a candidate metastasis inducer. Overall design: PB-Seq in 16 different primary tumours, 3 lung metastases, 6 lung macro-metastases and 9 LM cell lines to candidate genes enriched at metastatic sites compared to tumours.
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2021-04-17
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