Tumour takes after depletion of CD4+ cells, CD8+ cells and/or NK cells in the effector phase in BALB/c and C57Bl/6 mice, respectively, as well as tumour takes in C57Bl/6 knock-out mice.
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Mice were immunized with Her2MPtVLPs and 2 weeks later challenged with 5×104 D2F2/E2 cells (BALB/c) or 1–2×103 EL4-Her2 cells (C57Bl/6). P-values were calculated using Fisher's exact two-tailed test for BALB/c mice depleted of different cells as well as for C57Bl/6 knock-out mice while Peto-Peto-Wilcoxon was used for C57Bl/6 mice depleted of various cell types.acompared to unimmunized mice.bcompared to non-depleted immunized mice.cexperiment.dnot significant.eC57Bl/6 mice.fknock-out.
创建时间:
2015-12-02



