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Identification of telomeres associated RNAs by enChIP technology

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NIAID Data Ecosystem2026-03-10 收录
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We report isolation of telomeres by engineered DNA-binding molecule-mediated chromatin immunoprecipitation (enChIP) using a transcription activator-like (TAL) protein recognizing telomere repeats. Telomeres recognized by the tagged TAL protein were immunoprecipitated with an antibody against the tag and subjected to identification of telomere-binding molecules. enChIPed RNA-seq targeting telomeres identified known and novel telomere-associating transcripts.

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2017-09-17
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