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Antagonizing miR-128 abrogates chemoresistance-associated metastasis and is therapeutic in non-small cell lung cancer

NIAID Data Ecosystem2026-03-11 收录

非小细胞肺癌耐药性

miRNA治疗靶点

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE67729 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2019-06-25

炎症性肠病分子机制

miRNA治疗靶点

IntroductionInflammatory bowel disease (IBD) is a chronic disease involving multiple genes, and the current available targeted drugs for IBD only deliver moderate efficacy. Whether there is a single g

NIAID Data Ecosystem30

Disturbance of the let-7/LIN28 double-negative feedback loop is associated with radio- and chemo-resistance in non-small cell lung cancer

非小细胞肺癌耐药性

生物标志物预测

Radio- and chemo-resistance represent major obstacles in the therapy of non-small-cell lung cancer (NSCLC) and the underlying molecular mechanisms are not known. In the present study, during induction

NIAID Data Ecosystem20

Deregulation of the MiR-193b-KRAS Axis Contributes to Impaired Cell Growth in Pancreatic Cancer

癌症分子机制

miRNA治疗靶点

Modulation of KRAS activity by upstream signals has revealed a promising new approach for pancreatic cancer therapy; however, it is not clear whether microRNA-associated KRAS axis is involved in the c

Figshare2016-01-15 更新10

EGFR kinase domain T790M mutant in complex with a covalent aminobenzimidazole inhibitor.

EGFR抑制剂设计

非小细胞肺癌耐药性

EGFR kinase domain T790M mutant in complex with a covalent aminobenzimidazole inhibitor. Descriptor: Epidermal growth factor receptor, ~{N}-[7-methyl-1-[(3~{R})-1-propanoylazepan-3-yl]benzimidazol-2-y

Protein Data Bank Japan2024-11-06 更新20

ER Stress Negatively Modulates the Expression of the miR-199a/214 Cluster to Regulates Tumor Survival and Progression in Human Hepatocellular Cancer

癌症分子机制

miRNA治疗靶点

BackgroundRecent studies have emphasized causative links between microRNAs (miRNAs) deregulation and tumor development. In hepatocellular carcinoma (HCC), more and more miRNAs were identified as diagn

NIAID Data Ecosystem10

Antagonizing miR-128 abrogates chemoresistance-associated metastasis and is therapeutic in non-small cell lung cancer

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