Circadian Rhythm of Gene Expression Patterns in Liver of Mouse. Mus musculus

Genes encoding the circadian pacemaker in the hypothalamic suprachiasmatic nuclei (SCN) of mammals have recently been identified, but the molecubasis of circadian timing in peripheral tissue is not well understood. We used a bead-based microarray to identify mouse liver transcripts that show circadian cycles of abundance under constant conditions. Keywords: Time course Overall design: microarray-based expression profiling of mRNA with triplicates in mouse liver for 48 hours at 4-hour intervals