Regression coefficients (mL/min per 1.73 m<sup>2</sup>) and 95% confidence intervals for the associations between 5-year changes in physical activity and cystatin C-based estimated glomerular filtration rate at the subsequent round, adjusted for attained time-varying covariates.
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Model 1: crude; Model 2: adjusted for age and sex; Model 3: model 2 and highest attained level of education and time-dependent smoking, alcohol consumption, body mass index and animal protein; Model 4: model 3 and time-dependent diabetes, hypertension, hypercholesterolemia and cardiovascular disease. Percentage of people in the various 5-year change groups: 17.05% becoming inactive, 1.54% staying inactive, 31.07% staying moderately (in)active, 35.90% staying active, 14.45% becoming active. Regression coefficients (mL/min per 1.73 m2) and 95% confidence intervals for the associations between 5-year changes in physical activity and cystatin C-based estimated glomerular filtration rate at the subsequent round, adjusted for attained time-varying covariates.



