SNPs associated with mandible phenotypes (PCs).

Principal component (PC). Centroid size (CS). %varMand is the proportion of variation in mandible shape explained by the SNP. This value was calculated in a multivariate regression of shape on the SNP genotype. The candidate genes were identified based on their role in bone morphogenesis (see methods). Empty cells (-) mean no clear candidate gene emerged. The total set of genes in the QTL regions is shown in S5 Table† Regions that overlap with Maga et al 2015‡ Region that overlap with Pallares et al 2014* Regions that overlap with Attanasio et al 2014 using a window of 500Kb around the focal SNP** Regions that overlap with Attanasio et al 2014 using a window of 1Mb around the focal SNPColumns of the table show the SNP with the lowest p-value per QTL, its base-pair position, p-value calculated in GEMMA, and the proportion of total skull shape variation explained by the SNP (%varMand).