To systematically study the functions of metabolic genes in regulating anti-tumor immunity, we performed a series of in vivo metabolic-wide CRISPR screens in orthotopic lung tumor mice models. We cons
Aberrant activation of the Wnt/β-catenin signaling is associated with tumor development, and blocking β-catenin/BCL9 is a novel strategy for oncogenic Wnt/β-catenin signaling. Herein, we presented two
This cross-sectional study examined how maternal SARS-CoV-2 infection during pregnancy alters fetal placental macrophage programming, with implications for offspring neurodevelopment. Term placentas w
Single-cell RNA-Sequencing Data and analysis code used for analyses performed in the manuscript "Fc-enhanced anti-CTLA-4 depletes tumor-infiltrating regulatory T cells to augment immune effects of and